The pace of change across the health care landscape can be described as “dynamic,” “unprecedented,”“innovative,” and some might even add “tumultuous.” What cannot be debated is that the rapid advances in technology are contributing significantly to changes in clinical care, to the education of health care providers and the speed at which research outcomes can be translated into clinical practice. Clinical practices and health outcomes will be increasingly influenced and supported by innovative technologies, data analytics, and informatics. Medical ethicists will continue to face new challenges as the use of artificial intelligence grows. Whether caring for neonates or the growing aging population, improving health outcomes and quality of life are essential goals.